Off on a Tangent: Thalamocortical Axons Traverse a Permissive Corridor across the Basal Telencephalon

نویسندگان

  • Asif M. Maroof
  • Stewart A. Anderson
چکیده

The forebrain is one of most complex cellular structures known. Two phenomena that enable this complexity are tangential migrations that mix neurons from distinct progenitor fields, and axon guidance across intervening, noninnervated fields. A new paper in Cell by López-Bendito et al. has discovered the convergence of these phenomena in the critical thalamocortical system.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Tangential Neuronal Migration Controls Axon Guidance: A Role for Neuregulin-1 in Thalamocortical Axon Navigation

Neuronal migration and axon guidance constitute fundamental processes in brain development that are generally studied independently. Although both share common mechanisms of cell biology and biochemistry, little is known about their coordinated integration in the formation of neural circuits. Here we show that the development of the thalamocortical projection, one of the most prominent tracts i...

متن کامل

07-P017 Sumoylation modulates Spalt activity

embryogenesis, the ventral telencephalon (VT) plays a major role in the early development of these tracts. First, two populations of pioneer neurons allow corticothalamic (CTA) and thalamocortical axons (TCA) to enter the VT. Secondly, the VT forms a permissive corridor which guides TCAs through the MGE. Finally, thalamortical and corticothalamic axons guide each other once they have met in the...

متن کامل

07-P016 Multiple functions of Mitf in the melanophore development

embryogenesis, the ventral telencephalon (VT) plays a major role in the early development of these tracts. First, two populations of pioneer neurons allow corticothalamic (CTA) and thalamocortical axons (TCA) to enter the VT. Secondly, the VT forms a permissive corridor which guides TCAs through the MGE. Finally, thalamortical and corticothalamic axons guide each other once they have met in the...

متن کامل

07-P018 Analysis of Hox-cofactor interactions in living Drosophila embryos by the BiFC approach

embryogenesis, the ventral telencephalon (VT) plays a major role in the early development of these tracts. First, two populations of pioneer neurons allow corticothalamic (CTA) and thalamocortical axons (TCA) to enter the VT. Secondly, the VT forms a permissive corridor which guides TCAs through the MGE. Finally, thalamortical and corticothalamic axons guide each other once they have met in the...

متن کامل

07-P015 – Withdrawn

embryogenesis, the ventral telencephalon (VT) plays a major role in the early development of these tracts. First, two populations of pioneer neurons allow corticothalamic (CTA) and thalamocortical axons (TCA) to enter the VT. Secondly, the VT forms a permissive corridor which guides TCAs through the MGE. Finally, thalamortical and corticothalamic axons guide each other once they have met in the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Neuron

دوره 50  شماره 

صفحات  -

تاریخ انتشار 2006